The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD+
نویسندگان
چکیده
منابع مشابه
Proteolytically Coordinated Activation of Toxin-Antitoxin Modules
Chronic bacterial infections present a serious threat to the health of humans by decreasing life expectancy and quality. Resilience of these populations is closely linked to a small fraction of persister cells that are capable of surviving a wide range of environmental stressors that include starvation, DNA damage, heat shock, and antibiotics. In contrast to inherited resistance, persistence ar...
متن کاملStudies of the Reticuloendothelial System (res). 3. Blockade of the Res in Man.
In a previous communication (1), we have presented data indicating that the phagocytic capacity of the reticuloendotheial system (RES) in man can be determined safely and effectively by measuring the rate of disappearance of various doses of radioisotopically labeled aggregated human serum albumin particles from the blood after intravenous injection. Subsequently we reported that in patients wi...
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For many centuries, a predominant view of meaning was that the meaning of a word is some kind of chunk of mind-stuff (“idea”) glued to the word and animating it. However, while the traditional view was that we must first understand meaning, which enables us to understand language and hence our linguistic practices, a new approach to semantics that has emerged in the second half of the twentieth...
متن کاملSuppression of antibody formation by the RES-blockade. II. Effects of the RES-blockade with radioactive gold colloid.
For the purpose of revealing the interaction between macrophages and plasma cells in relation to antibody formation and information for cell specialization, the proliferation of plasma cell by antigenic stimulation was observed in the rats whose RES had been previously injured by radiogold. The production of the circulating antibody was markedly suppressed by the pretreatment with radiogold. Hi...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2018
ISSN: 0950-382X
DOI: 10.1111/mmi.14150